It is not a good idea to run the Malwarebytes Premium program along with another antivirus product. Having more than one program monitoring your security in real-time will slow down your computer and can actually DECREASE your security. Once installed on your computer it will generate a popup up to three times a day asking you to buy an upgrade to the premium version for real time monitoring. Version 3.0 and higher of Malwarebytes acts less like a run-on-demand application and more like a super annoying antivirus wannabe program. For years we have recommended that our customers have MBAM installed on their computers to scan on demand. Malwarebytes is a useful tool for finding and removing malware when you are using cut-rate or free antivirus software.
We have been receiving a lot of calls in our Service Centers and on our Compute This Radio Show about the newest version of MBAM and the annoying Malwarebytes Premium Trial Expired popups it generates.